GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THYM | cis | rs6540731 | 1 | rs6540732 | chr1:212392486 | NEK2 | chr1:211836115-211848967:- | 0.18 | 4.87 | 4.48E-6 | Intelligence (childhood) |
| THYM | cis | rs6540731 | 1 | rs6540733 | chr1:212392953 | NEK2 | chr1:211836115-211848967:- | -0.17 | -4.36 | 3.27E-5 | Intelligence (childhood) |
| THYM | cis | rs6540731 | 1 | rs6540735 | chr1:212400760 | NEK2 | chr1:211836115-211848967:- | -0.17 | -4.53 | 1.74E-5 | Intelligence (childhood) |
| THYM | cis | rs6545883 | 1 | rs6545883 | chr2:61772257 | AHSA2 | chr2:61404553-61414058:+ | -0.49 | -4.62 | 1.19E-5 | Tuberculosis |
| THYM | cis | rs6545883 | 1 | rs6545883 | chr2:61772257 | C2orf74 | chr2:61372243-61391964:+ | 0.57 | 5.16 | 1.38E-6 | Tuberculosis |
| THYM | cis | rs9309473 | 1 | rs6546835 | chr2:73664715 | ALMS1P | chr2:73872046-73912692:+ | 0.58 | 4.7 | 8.77E-6 | Metabolite levels |
| THYM | cis | rs9309473 | 1 | rs6546836 | chr2:73677833 | ALMS1P | chr2:73872046-73912692:+ | 0.55 | 4.29 | 4.33E-5 | Metabolite levels |
| THYM | cis | rs9309473 | 1 | rs6546837 | chr2:73677898 | ALMS1P | chr2:73872046-73912692:+ | 0.58 | 4.72 | 8.0E-6 | Metabolite levels |
| THYM | cis | rs9309473 | 1 | rs6546838 | chr2:73679280 | ALMS1P | chr2:73872046-73912692:+ | 0.58 | 4.72 | 8.0E-6 | Metabolite levels |
| THYM | cis | rs9309473 | 1 | rs6546839 | chr2:73680508 | ALMS1P | chr2:73872046-73912692:+ | 0.58 | 4.72 | 8.0E-6 | Metabolite levels |
| THYM | cis | rs4372836 | 1 | rs6547872 | chr2:28978074 | TRMT61B | chr2:29072690-29093175:- | -0.49 | -4.14 | 7.61E-5 | Body mass index |
| THYM | cis | rs7822232 | 1 | rs6558296 | chr8:145143802 | KIAA1875 | chr8:145162629-145173218:+ | -0.89 | -4.75 | 7.28E-6 | Blood metabolite levels |
| THYM | cis | rs568617 | 1 | rs656980 | chr11:65656282 | CTSW | chr11:65647284-65651212:+ | -0.59 | -7.12 | 2.04E-10 | Crohn's disease |
| THYM | cis | rs568617 | 1 | rs656980 | chr11:65656282 | SNX32 | chr11:65601410-65621170:+ | 0.55 | 5.17 | 1.29E-6 | Crohn's disease |
| THYM | cis | rs703842 | 1 | rs6581155 | chr12:58178162 | FAM119B | chr12:58166383-58176323:+ | 0.42 | 5.8 | 8.55E-8 | Multiple sclerosis |